Log in to save to my catalogue

NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606...

NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179221563

NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock

About this item

Full title

NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock

Publisher

Australia: Wiley Subscription Services, Inc

Journal title

Clinical and experimental pharmacology & physiology, 2019-02, Vol.46 (2), p.173-182

Language

English

Formats

Publication information

Publisher

Australia: Wiley Subscription Services, Inc

More information

Scope and Contents

Contents

Summary
We have previously demonstrated that the activation of the spleen tyrosine kinase (Syk)/inhibitory‐κB (IκB)‐α/nuclear factor‐κB (NF‐κB) p65 signalling pathway contributes to hypotension and inflammatory response in a rat models of zymosan (ZYM)‐induced non‐septic shock. The purpose of this study was to further examine the possible mechan...

Alternative Titles

Full title

NF‐κB activation mediates LPS‐or zymosan‐induced hypotension and inflammation reversed by BAY61‐3606, a selective Syk inhibitor, in rat models of septic and non‐septic shock

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179221563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179221563

Other Identifiers

ISSN

0305-1870

E-ISSN

1440-1681

DOI

10.1111/1440-1681.13045

How to access this item