Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Pro...
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Prophylactic Anticonvulsants in the Treatment of Adults with Metastatic Brain Tumors
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United States: Oxford University Press
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English
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United States: Oxford University Press
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Abstract
TARGET POPULATIONS
Adults with solid brain metastases who have not experienced a seizure.
QUESTION 1
Do prophylactic antiepileptic drugs (AEDs) decrease the risk of seizures in nonsurgical patients with brain metastases who are otherwise seizure-free?
RECOMMENDATION
Level 3: Prophylactic AEDs are not recommended for patients with brain metastases who did not undergo surgical resection and are otherwise seizure-free.
QUESTION 2
Do prophylactic AEDs decrease the risk of seizures in patients with brain metastases and no prior history of seizures in the postoperative setting?
RECOMMENDATION
Level 3: Routine postcraniotomy AED use for seizure-free patients with brain metastases is not recommended.
The full guideline can be found at: https://www.cns.org/guidelines/guidelines-treatment-adults-metastatic-brain-tumors/chapter_8....
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Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Role of Prophylactic Anticonvulsants in the Treatment of Adults with Metastatic Brain Tumors
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TN_cdi_proquest_miscellaneous_2179314116
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179314116
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ISSN
0148-396X
E-ISSN
1524-4040
DOI
10.1093/neuros/nyy545
