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Mitochondrial complex III is essential for suppressive function of regulatory T cells

Mitochondrial complex III is essential for suppressive function of regulatory T cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179348940

Mitochondrial complex III is essential for suppressive function of regulatory T cells

About this item

Full title

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2019-01, Vol.565 (7740), p.495-499

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Regulatory T cells (T
reg
cells), a distinct subset of CD4
+
T cells, are necessary for the maintenance of immune self-tolerance and homeostasis
1
,
2
. Recent studies have demonstrated that T
reg
cells exhibit a unique metabolic profile, characterized by an increase in mitochondrial metabolism relative to other CD4

Alternative Titles

Full title

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179348940

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179348940

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0846-z

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