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Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting Ig...

Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting Ig...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179354554

Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG

About this item

Full title

Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2019-02, Vol.25 (2), p.312-322

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Primary tumors may create the premetastatic niche in secondary organs for subsequent metastasis. Humoral immunity contributes to the progression of certain cancers, but the roles of B cells and their derived antibodies in premetastatic niche formation are poorly defined. Using a mouse model of spontaneous lymph node metastasis of breast cancer, we...

Alternative Titles

Full title

Tumor-educated B cells selectively promote breast cancer lymph node metastasis by HSPA4-targeting IgG

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179354554

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179354554

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/s41591-018-0309-y

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