The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling ne...
The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
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Author / Creator
Cheng, Maosheng , Sheng, Lu , Gao, Qian , Xiong, Qiuchan , Zhang, Haojie , Wu, Mingqing , Liang, Yu , Zhu, Fengyu , Zhang, Yingyin , Zhang, Xiuhong , Yuan, Quan and Li, Yang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
N
6
-methyladenosine (m6A) is the most abundant modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in many bioprocesses. However, its functions in bladder cancer (BCa) remain elusive. Here, we discovered that methyltransferase-like 3 (METTL3), a major RNA
N
6
-adenosine methyltransferase, was significantly u...
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Full title
The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network
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TN_cdi_proquest_miscellaneous_2179366700
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179366700
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-0683-z
