Interferons α and β in cancer: therapeutic opportunities from new insights
Interferons α and β in cancer: therapeutic opportunities from new insights
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Over the past decade, preclinical and clinical research have confirmed the essential role of interferons for effective host immunological responses to malignant cells. Type I interferons (IFNα and IFNβ) directly regulate transcription of >100 downstream genes, which results in a myriad of direct (on cancer cells) and indirect (through immune effect...
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Interferons α and β in cancer: therapeutic opportunities from new insights
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TN_cdi_proquest_miscellaneous_2179446478
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179446478
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ISSN
1474-1776
E-ISSN
1474-1784
DOI
10.1038/s41573-018-0011-2
