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PU.1 controls fibroblast polarization and tissue fibrosis

PU.1 controls fibroblast polarization and tissue fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179515343

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Fibroblasts are polymorphic cells with pleiotropic roles in organ morphogenesis, tissue homeostasis and immune responses. In fibrotic diseases, fibroblasts synthesize abundant amounts of extracellular matrix, which induces scarring and organ failure. By contrast, a hallmark feature of fibroblasts in arthritis is degradation of the extracellular mat...

Alternative Titles

Full title

PU.1 controls fibroblast polarization and tissue fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2179515343

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2179515343

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-019-0896-x

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