Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation
Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation
About this item
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
In cancer patients, metastasis of tumors to sentinel lymph nodes (LNs) predicts disease progression and often guides treatment decisions. The mechanisms underlying tumor LN metastasis are poorly understood. By using comparative transcriptomics and metabolomics analyses of primary and LN-metastatic tumors in mice, we found that LN metastasis require...
Alternative Titles
Full title
Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_2183640276
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2183640276
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aav0173
