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Obstetric complication-associated ANXA5 promoter polymorphisms may affect gene expression via DNA se...

Obstetric complication-associated ANXA5 promoter polymorphisms may affect gene expression via DNA se...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2185561914

Obstetric complication-associated ANXA5 promoter polymorphisms may affect gene expression via DNA secondary structures

About this item

Full title

Obstetric complication-associated ANXA5 promoter polymorphisms may affect gene expression via DNA secondary structures

Publisher

England: Nature Publishing Group

Journal title

Journal of human genetics, 2019-05, Vol.64 (5), p.459-466

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

Recent findings have highlighted the possibility that polymorphisms within the annexin A5 gene (ANXA5) promoter contribute to the etiology of various obstetric complications. However, the underlying mechanisms are unknown. The M2 haplotype of the ANXA5 shows lower activity and less expression of ANXA5 mRNA. This gene promoter region has a motif tha...

Alternative Titles

Full title

Obstetric complication-associated ANXA5 promoter polymorphisms may affect gene expression via DNA secondary structures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2185561914

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2185561914

Other Identifiers

ISSN

1434-5161

E-ISSN

1435-232X

DOI

10.1038/s10038-019-0578-4

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