Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling
Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling
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Author / Creator
Dong, Hai-Chao , Li, Pei-Nan , Chen, Chang-Jian , Xu, Xin , Zhang, Hong , Liu, Gang , Zheng, Lian-Jie and Li, Peng
Publisher
New York: Springer US
Journal title
Language
English
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Publisher
New York: Springer US
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Scope and Contents
Contents
Sinomenine (SIN) has been shown to protect against IL-1β-induced chondrocyte apoptosis
in vitro
. However, the role of SIN in the anterior cruciate ligament transection (ACLT)-induced osteoarthritis (OA) mouse model and its underlying molecular mechanisms remain unclear. In the present study, the protective effect of SIN on ACLT-induced artic...
Alternative Titles
Full title
Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling
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Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_2189530123
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2189530123
Other Identifiers
ISSN
0360-3997
E-ISSN
1573-2576
DOI
10.1007/s10753-019-00986-3