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Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2189530123

Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

About this item

Full title

Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

Publisher

New York: Springer US

Journal title

Inflammation, 2019-08, Vol.42 (4), p.1265-1275

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Sinomenine (SIN) has been shown to protect against IL-1β-induced chondrocyte apoptosis
in vitro
. However, the role of SIN in the anterior cruciate ligament transection (ACLT)-induced osteoarthritis (OA) mouse model and its underlying molecular mechanisms remain unclear. In the present study, the protective effect of SIN on ACLT-induced artic...

Alternative Titles

Full title

Sinomenine Attenuates Cartilage Degeneration by Regulating miR-223-3p/NLRP3 Inflammasome Signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2189530123

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2189530123

Other Identifiers

ISSN

0360-3997

E-ISSN

1573-2576

DOI

10.1007/s10753-019-00986-3

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