Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
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Full title
Author / Creator
Yan, Renhong , Zhao, Xin , Lei, Jianlin and Zhou, Qiang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The L-type amino acid transporter 1 (LAT1; also known as SLC7A5) catalyses the cross-membrane flux of large neutral amino acids in a sodium- and pH-independent manner
1
–
3
. LAT1, an antiporter of the amino acid–polyamine–organocation superfamily, also catalyses the permeation of thyroid hormones, pharmaceutical drugs, and hormone prec...
Alternative Titles
Full title
Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
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Record Identifier
TN_cdi_proquest_miscellaneous_2191360756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2191360756
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1011-z
