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Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibiti...

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibiti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2195270196

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway

About this item

Full title

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway

Publisher

Greece: Spandidos Publications

Journal title

Oncology reports, 2019-05, Vol.41 (5), p.2937-2944

Language

English

Formats

Publication information

Publisher

Greece: Spandidos Publications

More information

Scope and Contents

Contents

Timosaponin A‑III (TAIII) is a saponin isolated from anemarrhena asphodeloides and possesses the inhibitory effect on proliferation of multiple tumor cells. In the present study, the antitumor effect of TAIII and its underlying molecular mechanisms were investigated in vitro in T‑cell acute lymphoblastic leukemia (T‑ALL) Jurkat cells. The results d...

Alternative Titles

Full title

Timosaponin A‑III induces autophagy of T‑cell acute lymphoblastic leukemia Jurkat cells via inhibition of the PI3K/Akt/mTOR pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2195270196

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2195270196

Other Identifiers

ISSN

1021-335X

E-ISSN

1791-2431

DOI

10.3892/or.2019.7072

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