Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cance...
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
About this item
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Author / Creator
Malehmir, Mohsen , Pfister, Dominik , Gallage, Suchira , Szydlowska, Marta , Inverso, Donato , Kotsiliti, Elena , Leone, Valentina , Peiseler, Moritz , Surewaard, Bas G. J. , Rath, Dominik , Ali, Adnan , Wolf, Monika Julia , Drescher, Hannah , Healy, Marc E. , Dauch, Daniel , Kroy, Daniela , Krenkel, Oliver , Kohlhepp, Marlene , Engleitner, Thomas , Olkus, Alexander , Sijmonsma, Tjeerd , Volz, Julia , Deppermann, Carsten , Stegner, David , Helbling, Patrick , Nombela-Arrieta, César , Rafiei, Anahita , Hinterleitner, Martina , Rall, Marcel , Baku, Florian , Borst, Oliver , Wilson, Caroline L. , Leslie, Jack , O’Connor, Tracy , Weston, Christopher J. , Chauhan, Abhishek , Adams, David H. , Sheriff, Lozan , Teijeiro, Ana , Prinz, Marco , Bogeska, Ruzhica , Anstee, Natasha , Bongers, Malte N. , Notohamiprodjo, Mike , Geisler, Tobias , Withers, Dominic J. , Ware, Jerry , Mann, Derek A. , Augustin, Hellmut G. , Vegiopoulos, Alexandros , Milsom, Michael D. , Rose, Adam J. , Lalor, Patricia F. , Llovet, Josep M. , Pinyol, Roser , Tacke, Frank , Rad, Roland , Matter, Matthias , Djouder, Nabil , Kubes, Paul , Knolle, Percy A. , Unger, Kristian , Zender, Lars , Nieswandt, Bernhard , Gawaz, Meinrad , Weber, Achim and Heikenwalder, Mathias
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis (NASH), potentially progressing to cirrhosis and hepatocellular carcinoma (HCC). Here, we show that platelet number, platelet activation and platelet aggregation are increased in NASH but not in steatosis or insulin resistance. Antiplatelet therapy (APT; aspiri...
Alternative Titles
Full title
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Authors, Artists and Contributors
Author / Creator
Pfister, Dominik
Gallage, Suchira
Szydlowska, Marta
Inverso, Donato
Kotsiliti, Elena
Leone, Valentina
Peiseler, Moritz
Surewaard, Bas G. J.
Rath, Dominik
Ali, Adnan
Wolf, Monika Julia
Drescher, Hannah
Healy, Marc E.
Dauch, Daniel
Kroy, Daniela
Krenkel, Oliver
Kohlhepp, Marlene
Engleitner, Thomas
Olkus, Alexander
Sijmonsma, Tjeerd
Volz, Julia
Deppermann, Carsten
Stegner, David
Helbling, Patrick
Nombela-Arrieta, César
Rafiei, Anahita
Hinterleitner, Martina
Rall, Marcel
Baku, Florian
Borst, Oliver
Wilson, Caroline L.
Leslie, Jack
O’Connor, Tracy
Weston, Christopher J.
Chauhan, Abhishek
Adams, David H.
Sheriff, Lozan
Teijeiro, Ana
Prinz, Marco
Bogeska, Ruzhica
Anstee, Natasha
Bongers, Malte N.
Notohamiprodjo, Mike
Geisler, Tobias
Withers, Dominic J.
Ware, Jerry
Mann, Derek A.
Augustin, Hellmut G.
Vegiopoulos, Alexandros
Milsom, Michael D.
Rose, Adam J.
Lalor, Patricia F.
Llovet, Josep M.
Pinyol, Roser
Tacke, Frank
Rad, Roland
Matter, Matthias
Djouder, Nabil
Kubes, Paul
Knolle, Percy A.
Unger, Kristian
Zender, Lars
Nieswandt, Bernhard
Gawaz, Meinrad
Weber, Achim
Heikenwalder, Mathias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2202194496
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2202194496
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-019-0379-5
