ALIX increases protein content and protective function of iPSC-derived exosomes
ALIX increases protein content and protective function of iPSC-derived exosomes
About this item
Full title
Author / Creator
Sun, Ruiting , Liu, Yingying , Lu, Meng , Ding, Qianqian , Wang, Pingping , Zhang, Heng , Tian, Xiaoyu , Lu, Peng , Meng, Dan , Sun, Ning , Xiang, Meng and Chen, Sifeng
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Nature of exosome-secreting cells determines exosome content and function. ALIX, involved in exosome biogenesis, promotes cell degeneration. Here, ALIX was knocked out (iPSC-ALIX
−/−
) and overexpressed (iPSC-ALIX
3+
) in induced pluripotent stem cells (iPSCs) using CRISPR-Cas9 and lentiviral transduction, respectively, and the secreted...
Alternative Titles
Full title
ALIX increases protein content and protective function of iPSC-derived exosomes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2203136425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2203136425
Other Identifiers
ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-019-01767-z
