Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT
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Author / Creator
Fitzgerald, Sean T , Wang, Shunli , Dai, Daying , Douglas, Andrew , Kadirvel, Ramanathan , Gounis, Matthew J , Chueh, Juyu , Puri, Ajit S , Layton, Kennith F , Thacker, Ike C , Hanel, Ricardo A , Sauvageau, Eric , Aghaebrahim, Amin , Almekhlafi, Mohammed A , Demchuk, Andrew M , Nogueira, Raul G , Pereira, Vitor M , Kvamme, Peter , Kayan, Yasha , Delgado Almandoz, Josser E , Yoo, Albert J , Kallmes, David F , Doyle, Karen M and Brinjikji, Waleed
Publisher
England: BMJ Publishing Group LTD
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Language
English
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Publisher
England: BMJ Publishing Group LTD
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Contents
BackgroundCurrent studies on clot characterization in acute ischemic stroke focus on fibrin and red blood cell composition. Few studies have examined platelet composition in acute ischemic stroke clots. We characterize clot composition using the Martius Scarlet Blue stain and assess associations between platelet density and CT density.Materials and methodHistopathological analysis of the clots collected as part of the multi-institutional STRIP registry was performed using Martius Scarlet Blue stain and the composition of the clots was quantified using Orbit Image Analysis (www.orbit.bio) machine learning software. Prior to endovascular treatment, each patient underwent non-contrast CT (NCCT) and the CT density of each clot was measured. Correlations between clot components and clinical information were assessed using the χ2 test.ResultsEighty-five patients were included in the study. The mean platelet density of the clots was...
Alternative Titles
Full title
Platelet-rich clots as identified by Martius Scarlet Blue staining are isodense on NCCT
Authors, Artists and Contributors
Author / Creator
Wang, Shunli
Dai, Daying
Douglas, Andrew
Kadirvel, Ramanathan
Gounis, Matthew J
Chueh, Juyu
Puri, Ajit S
Layton, Kennith F
Thacker, Ike C
Hanel, Ricardo A
Sauvageau, Eric
Aghaebrahim, Amin
Almekhlafi, Mohammed A
Demchuk, Andrew M
Nogueira, Raul G
Pereira, Vitor M
Kvamme, Peter
Kayan, Yasha
Delgado Almandoz, Josser E
Yoo, Albert J
Kallmes, David F
Doyle, Karen M
Brinjikji, Waleed
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2204697000
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2204697000
Other Identifiers
ISSN
1759-8478
E-ISSN
1759-8486
DOI
10.1136/neurintsurg-2018-014637
