SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to ob...
SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity
About this item
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Author / Creator
Keiran, Noelia , Ceperuelo-Mallafré, Victoria , Calvo, Enrique , Hernández-Alvarez, Maria Isabel , Ejarque, Miriam , Núñez-Roa, Catalina , Horrillo, Daniel , Maymó-Masip, Elsa , Rodríguez, M. Mar , Fradera, Rosa , de la Rosa, Juan Vladimir , Jorba, Rosa , Megia, Ana , Zorzano, Antonio , Medina-Gómez, Gema , Serena, Carolina , Castrillo, Antonio , Vendrell, Joan and Fernández-Veledo, Sonia
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Succinate is a signaling metabolite sensed extracellularly by succinate receptor 1 (SUNCR1). The accumulation of succinate in macrophages is known to activate a pro-inflammatory program; however, the contribution of SUCNR1 to macrophage phenotype and function has remained unclear. Here we found that activation of SUCNR1 had a critical role in the a...
Alternative Titles
Full title
SUCNR1 controls an anti-inflammatory program in macrophages to regulate the metabolic response to obesity
Authors, Artists and Contributors
Author / Creator
Ceperuelo-Mallafré, Victoria
Calvo, Enrique
Hernández-Alvarez, Maria Isabel
Ejarque, Miriam
Núñez-Roa, Catalina
Horrillo, Daniel
Maymó-Masip, Elsa
Rodríguez, M. Mar
Fradera, Rosa
de la Rosa, Juan Vladimir
Jorba, Rosa
Megia, Ana
Zorzano, Antonio
Medina-Gómez, Gema
Serena, Carolina
Castrillo, Antonio
Vendrell, Joan
Fernández-Veledo, Sonia
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2206224948
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2206224948
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0372-7
