Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthe...
Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthetase 2 (OAS2)
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Canada: NRC Research Press
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Language
English
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Canada: NRC Research Press
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Human 2'-5' oligoadenylate synthetases (OAS) are a family of interferon-inducible proteins that, upon activation by double-stranded RNA, polymerize ATP into 2'-5' linked oligoadenylates. In this study, we probed the RNA cofactor specificity of the two smallest isozymes, OAS1 and OAS2. First, we developed a strategy for the expression and purificati...
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Full title
Impact of double-stranded RNA characteristics on the activation of human 2'-5'-oligoadenylate synthetase 2 (OAS2)
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TN_cdi_proquest_miscellaneous_2207161581
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2207161581
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ISSN
0829-8211
E-ISSN
1208-6002
DOI
10.1139/bcb-2019-0060
