Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
About this item
Full title
Author / Creator
Bolhaqueiro, Ana C. F. , Ponsioen, Bas , Bakker, Bjorn , Klaasen, Sjoerd J. , Kucukkose, Emre , van Jaarsveld, Richard H. , Vivié, Judith , Verlaan-Klink, Ingrid , Hami, Nizar , Spierings, Diana C. J. , Sasaki, Nobuo , Dutta, Devanjali , Boj, Sylvia F. , Vries, Robert G. J. , Lansdorp, Peter M. , van de Wetering, Marc , van Oudenaarden, Alexander , Clevers, Hans , Kranenburg, Onno , Foijer, Floris , Snippert, Hugo J. G. and Kops, Geert J. P. L.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Chromosome segregation errors cause aneuploidy and genomic heterogeneity, which are hallmarks of cancer in humans. A persistent high frequency of these errors (chromosomal instability (CIN)) is predicted to profoundly impact tumor evolution and therapy response. It is unknown, however, how prevalent CIN is in human tumors. Using three-dimensional l...
Alternative Titles
Full title
Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids
Authors, Artists and Contributors
Author / Creator
Ponsioen, Bas
Bakker, Bjorn
Klaasen, Sjoerd J.
Kucukkose, Emre
van Jaarsveld, Richard H.
Vivié, Judith
Verlaan-Klink, Ingrid
Hami, Nizar
Spierings, Diana C. J.
Sasaki, Nobuo
Dutta, Devanjali
Boj, Sylvia F.
Vries, Robert G. J.
Lansdorp, Peter M.
van de Wetering, Marc
van Oudenaarden, Alexander
Clevers, Hans
Kranenburg, Onno
Foijer, Floris
Snippert, Hugo J. G.
Kops, Geert J. P. L.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2217469235
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2217469235
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/s41588-019-0399-6
