Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative st...
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress
About this item
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Author / Creator
Wang, Jun , Wu, Qi and Qiu, Jianxin
Publisher
New York: Elsevier Inc
Journal title
Language
English
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Publication information
Publisher
New York: Elsevier Inc
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Scope and Contents
Contents
Clear cell renal cell carcinoma (ccRCC) is characterized by the activation of hypoxia-inducible factors and enhanced aerobic glycolysis. In our previous study, metabolic profiling revealed a threefold increase of fructose 1,6-bisphosphate (FBP) in ccRCC tissue compared with normal kidney tissue. As an important intermediate metabolite, its role in...
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Full title
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress
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Record Identifier
TN_cdi_proquest_miscellaneous_2229097405
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2229097405
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/s41374-019-0203-3