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Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative st...

Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative st...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2229097405

Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress

About this item

Full title

Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress

Author / Creator

Publisher

New York: Elsevier Inc

Journal title

Laboratory investigation, 2019-06, Vol.99 (6), p.898-908

Language

English

Formats

Publication information

Publisher

New York: Elsevier Inc

More information

Scope and Contents

Contents

Clear cell renal cell carcinoma (ccRCC) is characterized by the activation of hypoxia-inducible factors and enhanced aerobic glycolysis. In our previous study, metabolic profiling revealed a threefold increase of fructose 1,6-bisphosphate (FBP) in ccRCC tissue compared with normal kidney tissue. As an important intermediate metabolite, its role in...

Alternative Titles

Full title

Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2229097405

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2229097405

Other Identifiers

ISSN

0023-6837

E-ISSN

1530-0307

DOI

10.1038/s41374-019-0203-3

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