Clinical and analytical validation of Ki-67 in 9069 patients from IBCSG VIII + IX, BIG1-98 and Gepar...
Clinical and analytical validation of Ki-67 in 9069 patients from IBCSG VIII + IX, BIG1-98 and GeparTrio trial: systematic modulation of interobserver variance in a comprehensive in silico ring trial
About this item
Full title
Author / Creator
Denkert, Carsten , Budczies, Jan , Regan, Meredith M. , Loibl, Sibylle , Dell’Orto, Patrizia , von Minckwitz, Gunter , Mastropasqua, Mauro G. , Solbach, Christine , Thürlimann, Beat , Mehta, Keyur , Blohmer, Jens-Uwe , Colleoni, Marco , Müller, Volkmar , Klauschen, Frederick , Ataseven, Beyhan , Engels, Knut , Kammler, Roswitha , Pfitzner, Berit M. , Dietel, Manfred , Fasching, Peter A. and Viale, Giuseppe
Publisher
New York: Springer US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Springer US
Subjects
More information
Scope and Contents
Contents
Purpose
Ki-67 has been clinically validated for risk assessment in breast cancer, but the analytical validation and cutpoint-definition remain a challenge. Intraclass correlation coefficients (ICCs) are a statistical parameter for Ki-67 interobserver performance. However, the maximum degree of variance among pathologists allowed for meaningful b...
Alternative Titles
Full title
Clinical and analytical validation of Ki-67 in 9069 patients from IBCSG VIII + IX, BIG1-98 and GeparTrio trial: systematic modulation of interobserver variance in a comprehensive in silico ring trial
Authors, Artists and Contributors
Author / Creator
Budczies, Jan
Regan, Meredith M.
Loibl, Sibylle
Dell’Orto, Patrizia
von Minckwitz, Gunter
Mastropasqua, Mauro G.
Solbach, Christine
Thürlimann, Beat
Mehta, Keyur
Blohmer, Jens-Uwe
Colleoni, Marco
Müller, Volkmar
Klauschen, Frederick
Ataseven, Beyhan
Engels, Knut
Kammler, Roswitha
Pfitzner, Berit M.
Dietel, Manfred
Fasching, Peter A.
Viale, Giuseppe
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2231890283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231890283
Other Identifiers
ISSN
0167-6806
E-ISSN
1573-7217
DOI
10.1007/s10549-018-05112-9
