Phase separation drives X-chromosome inactivation: a hypothesis
Phase separation drives X-chromosome inactivation: a hypothesis
About this item
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The long non-coding RNA
Xist
induces heterochromatinization of the X chromosome by recruiting repressive protein complexes to chromatin. Here we gather evidence, from the literature and from computational analyses, showing that
Xist
assemblies are similar in size, shape and composition to phase-separated condensates, such as paraspeckle...
Alternative Titles
Full title
Phase separation drives X-chromosome inactivation: a hypothesis
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Record Identifier
TN_cdi_proquest_miscellaneous_2231892018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231892018
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-019-0223-0
