HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
About this item
Full title
Author / Creator
Xu, Chang , Ooi, Wen Fong , Qamra, Aditi , Tan, Jing , Chua, Benjamin Yan-Jiang , Ho, Shamaine Wei Ting , Das, Kakoli , Adam Isa, Zul Fazreen , Li, Zhimei , Yao, Xiaosai , Yan, Tingdong , Xing, Manjie , Huang, Kie Kyon , Lin, Joyce Suling , Nandi, Tannistha , Tay, Su Ting , Lee, Ming Hui , Tan, Angie Lay Keng , Ong, Xuewen , Ashktorab, Hassan , Smoot, Duane , Li, Shang , Ng, Shyh-Chang , Teh, Bin Tean and Tan, Patrick
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
ObjectiveGastric cancer (GC) is a leading cause of cancer mortality. Previous studies have shown that hepatocyte nuclear factor-4α (HNF4α) is specifically overexpressed in GC and functionally required for GC development. In this study, we investigated, on a genome-wide scale, target genes of HNF4α and oncogenic pathways driven by HNF4α and HNF4α ta...
Alternative Titles
Full title
HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer
Authors, Artists and Contributors
Author / Creator
Ooi, Wen Fong
Qamra, Aditi
Tan, Jing
Chua, Benjamin Yan-Jiang
Ho, Shamaine Wei Ting
Das, Kakoli
Adam Isa, Zul Fazreen
Li, Zhimei
Yao, Xiaosai
Yan, Tingdong
Xing, Manjie
Huang, Kie Kyon
Lin, Joyce Suling
Nandi, Tannistha
Tay, Su Ting
Lee, Ming Hui
Tan, Angie Lay Keng
Ong, Xuewen
Ashktorab, Hassan
Smoot, Duane
Li, Shang
Ng, Shyh-Chang
Teh, Bin Tean
Tan, Patrick
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2231945155
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2231945155
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2018-318025
