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Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorecta...

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorecta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2232091376

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma

About this item

Full title

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma

Publisher

UK: Oxford University Press

Journal title

American journal of clinical pathology, 2019-06, Vol.152 (1), p.97-108

Language

English

Formats

Publication information

Publisher

UK: Oxford University Press

More information

Scope and Contents

Contents

ABSTRACT
Objectives
ERBB2 (human epidermal growth factor receptor 2 [HER2]) amplification/overexpression in colorectal carcinomas (CRCs) may predict response to HER2 inhibitors. We correlated ERBB2 amplification by next-generation sequencing (NGS) with HER2 overexpression by immunohistochemistry.
Methods
NGS was performed on specimens c...

Alternative Titles

Full title

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2232091376

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2232091376

Other Identifiers

ISSN

0002-9173

E-ISSN

1943-7722

DOI

10.1093/ajcp/aqz031

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