Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemothe...
Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial
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Author / Creator
West, Howard, MD , McCleod, Michael, DO , Hussein, Maen, MD , Morabito, Alessandro, MD , Rittmeyer, Achim, MD , Conter, Henry J, MD , Kopp, Hans-Georg, Prof , Daniel, Davey, MD , McCune, Steven, MD , Mekhail, Tarek, MD , Zer, Alona, Prof , Reinmuth, Niels, Prof , Sadiq, Ahad, MD , Sandler, Alan, MD , Lin, Wei, MD , Ochi Lohmann, Tania, PhD , Archer, Venice, MD , Wang, Lijia, PhD , Kowanetz, Marcin, MD and Cappuzzo, Federico, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundAtezolizumab (a monoclonal antibody against PD-L1), which restores anticancer immunity, improved overall survival in patients with previously treated non-small-cell lung cancer and also showed clinical benefit when combined with chemotherapy as first-line treatment of non-small-cell lung cancer. IMpower130 aimed to assess the effic...
Alternative Titles
Full title
Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial
Authors, Artists and Contributors
Author / Creator
McCleod, Michael, DO
Hussein, Maen, MD
Morabito, Alessandro, MD
Rittmeyer, Achim, MD
Conter, Henry J, MD
Kopp, Hans-Georg, Prof
Daniel, Davey, MD
McCune, Steven, MD
Mekhail, Tarek, MD
Zer, Alona, Prof
Reinmuth, Niels, Prof
Sadiq, Ahad, MD
Sandler, Alan, MD
Lin, Wei, MD
Ochi Lohmann, Tania, PhD
Archer, Venice, MD
Wang, Lijia, PhD
Kowanetz, Marcin, MD
Cappuzzo, Federico, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2232119706
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2232119706
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ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(19)30167-6