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GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2232120028

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies

About this item

Full title

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies

Publisher

New York: Springer US

Journal title

Molecular neurobiology, 2019-11, Vol.56 (11), p.7774-7788

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Galectin-8 (Gal-8) is a glycan-binding protein that modulates a variety of cellular processes interacting with cell surface glycoproteins. Neutralizing anti-Gal-8 antibodies that block Gal-8 functions have been described in autoimmune and inflammatory disorders, likely playing pathogenic roles. In the brain, Gal-8 is highly expressed in the choroid...

Alternative Titles

Full title

GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2232120028

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2232120028

Other Identifiers

ISSN

0893-7648

E-ISSN

1559-1182

DOI

10.1007/s12035-019-1621-3

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