Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines
Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Summary
Splicing of pre-mRNA into functional mRNA, carried out by the spliceosome, represents a crucial step in eukaryotic gene expression. Mutations and other deregulation in some of the spliceosome components have been identified in multiple pathologies, including hematological malignancies. In this context, we evaluated the therapeutic potent...
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Full title
Apoptosis induction and cell cycle arrest of pladienolide B in erythroleukemia cell lines
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TN_cdi_proquest_miscellaneous_2233862030
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2233862030
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ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1007/s10637-019-00796-2
