Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -res...
Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells
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Publisher
New York: Springer US
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Language
English
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Publisher
New York: Springer US
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Summary
Vitamin K
3
, also known as menadione, is a synthetic lipid-soluble 2-methyl-1,4- naphthoquinone analogs of vitamin K. The vitamin K derivatives exhibit potent cytotoxicity against several cancer cell lines through ROS induction and mitochondrial dysfunction. We investigated vitamin K
3
-inspired derivatives as potential apop...
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Full title
Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells
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TN_cdi_proquest_miscellaneous_2250628482
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2250628482
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ISSN
0167-6997
E-ISSN
1573-0646
DOI
10.1007/s10637-019-00810-7
