A 3D model of a human epiblast reveals BMP4-driven symmetry breaking
A 3D model of a human epiblast reveals BMP4-driven symmetry breaking
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Breaking the anterior–posterior symmetry in mammals occurs at gastrulation. Much of the signalling network underlying this process has been elucidated in the mouse; however, there is no direct molecular evidence of events driving axis formation in humans. Here, we use human embryonic stem cells to generate an in vitro three-dimensional model of a h...
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A 3D model of a human epiblast reveals BMP4-driven symmetry breaking
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TN_cdi_proquest_miscellaneous_2251105025
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2251105025
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ISSN
1465-7392,1476-4679
E-ISSN
1476-4679
DOI
10.1038/s41556-019-0349-7
