Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone
Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
Giant cell tumor of bone typically involves the epiphysis of the long bones of skeletally mature patients. It is genetically characterized by highly recurrent and specific mutations of the
H3F3A
gene, which encodes histone H3.3. The most common mutation H3F3A G34W can readily be detected by a recently developed mutation-specific antibody. Gia...
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Full title
Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone
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TN_cdi_proquest_miscellaneous_2254505709
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2254505709
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ISSN
0893-3952
E-ISSN
1530-0285
DOI
10.1038/s41379-019-0318-5
