Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice
Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice
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Matheoud, Diana , Cannon, Tyler , Voisin, Aurore , Penttinen, Anna-Maija , Ramet, Lauriane , Fahmy, Ahmed M. , Ducrot, Charles , Laplante, Annie , Bourque, Marie-Josée , Zhu, Lei , Cayrol, Romain , Le Campion, Armelle , McBride, Heidi M. , Gruenheid, Samantha , Trudeau, Louis-Eric and Desjardins, Michel
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Parkinson’s disease is a neurodegenerative disorder with motor symptoms linked to the loss of dopaminergic neurons in the substantia nigra compacta. Although the mechanisms that trigger the loss of dopaminergic neurons are unclear, mitochondrial dysfunction and inflammation are thought to have key roles
1
,
2
. An early-onset form of Pa...
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Full title
Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice
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TN_cdi_proquest_miscellaneous_2259906520
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2259906520
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1405-y