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Platycodin D inhibits proliferation, migration and induces chemosensitization through inactivation o...

Platycodin D inhibits proliferation, migration and induces chemosensitization through inactivation o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2265749506

Platycodin D inhibits proliferation, migration and induces chemosensitization through inactivation of the NF‐κB and JAK2/STAT3 pathways in multiple myeloma cells

About this item

Full title

Platycodin D inhibits proliferation, migration and induces chemosensitization through inactivation of the NF‐κB and JAK2/STAT3 pathways in multiple myeloma cells

Publisher

Australia: Wiley Subscription Services, Inc

Journal title

Clinical and experimental pharmacology & physiology, 2019-12, Vol.46 (12), p.1194-1200

Language

English

Formats

Publication information

Publisher

Australia: Wiley Subscription Services, Inc

More information

Scope and Contents

Contents

Multiple myeloma (MM) is a malignancy characterized by the proliferation of malignant plasma cells. Platycodin D (PLD) is a triterpenoid saponin that exerts anti‐tumour activity through multiple mechanisms. However, the role of PLD in MM remains unknown. Here, we investigated the effect of PLD on MM cell lines NCI‐H929 and U266B1, and elucidated th...

Alternative Titles

Full title

Platycodin D inhibits proliferation, migration and induces chemosensitization through inactivation of the NF‐κB and JAK2/STAT3 pathways in multiple myeloma cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2265749506

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2265749506

Other Identifiers

ISSN

0305-1870,1440-1681

E-ISSN

1440-1681

DOI

10.1111/1440-1681.13145

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