Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile e...
Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes
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Author / Creator
Bertrand, Denis , Shaw, Jim , Kalathiyappan, Manesh , Ng, Amanda Hui Qi , Kumar, M. Senthil , Li, Chenhao , Dvornicic, Mirta , Soldo, Janja Paliska , Koh, Jia Yu , Tong, Chengxuan , Ng, Oon Tek , Barkham, Timothy , Young, Barnaby , Marimuthu, Kalisvar , Chng, Kern Rei , Sikic, Mile and Nagarajan, Niranjan
Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Characterization of microbiomes has been enabled by high-throughput metagenomic sequencing. However, existing methods are not designed to combine reads from short- and long-read technologies. We present a hybrid metagenomic assembler named OPERA-MS that integrates assembly-based metagenome clustering with repeat-aware, exact scaffolding to accurate...
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Full title
Hybrid metagenomic assembly enables high-resolution analysis of resistance determinants and mobile elements in human microbiomes
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TN_cdi_proquest_miscellaneous_2267025206
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2267025206
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-019-0191-2
