Endometrial disorders represent a major gynaecological burden. Current research models fail to recapitulate the nature and heterogeneity of these diseases, thereby hampering scientific and clinical progress. Here we developed long-term expandable organoids from a broad spectrum of endometrial pathologies. Organoids from endometriosis show disease-a...

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

10.1038/s41556-019-0360-z