HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular c...
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Transcription factor PAX8 expression is upregulated in several types of cancers. However, little is known about the function of PAX8 in the progression of hepatoma and its regulatory mechanisms. Here, we show that PAX8 silencing inhibits the proliferation and clonogenicity of hepatoma cells and its growth in vivo. The HBV X protein (HBx) does not d...
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Full title
HBx regulates transcription factor PAX8 stabilization to promote the progression of hepatocellular carcinoma
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TN_cdi_proquest_miscellaneous_2270010617
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2270010617
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ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/s41388-019-0907-2
