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Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3–6 years and 2–35 m...

Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3–6 years and 2–35 m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2271846310

Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3–6 years and 2–35 months of age- an open-label, randomized phase IIb clinical trial

About this item

Full title

Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3–6 years and 2–35 months of age- an open-label, randomized phase IIb clinical trial

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2019-09, Vol.37 (37), p.5559-5566

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights•An inactivated EV-A71 vaccine is safe and immunogenic in children 2 months to 6 years of age. •Adjuvanted 1.0 μg total viral protein elicited higher titers of neutralizing antibody than adjuvanted 0.5 μg total protein. •Elicited neutralizing antibody could last for up to a year.

Alternative Titles

Full title

Immunogenicity and safety of an inactivated enterovirus A71 vaccine in children 3–6 years and 2–35 months of age- an open-label, randomized phase IIb clinical trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2271846310

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2271846310

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2019.07.096

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