Mechanisms of hypoxia signalling: new implications for nephrology
Mechanisms of hypoxia signalling: new implications for nephrology
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Studies of the regulation of erythropoietin (EPO) production by the liver and kidneys, one of the classical physiological responses to hypoxia, led to the discovery of human oxygen-sensing mechanisms, which are now being targeted therapeutically. The oxygen-sensitive signal is generated by 2-oxoglutarate-dependent dioxygenases that deploy molecular...
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Full title
Mechanisms of hypoxia signalling: new implications for nephrology
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TN_cdi_proquest_miscellaneous_2286940077
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2286940077
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ISSN
1759-5061
E-ISSN
1759-507X
DOI
10.1038/s41581-019-0182-z
