A nanoemulsion-adjuvanted intranasal H5N1 influenza vaccine protects ferrets against homologous and...
A nanoemulsion-adjuvanted intranasal H5N1 influenza vaccine protects ferrets against homologous and heterologous H5N1 lethal challenge
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Netherlands: Elsevier Ltd
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English
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Netherlands: Elsevier Ltd
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AbstractBackgroundFlu vaccines administered intramuscularly (IM) have shown seasonally fluctuating efficacy, 20–60%, throughout the last 15 years. We formulated a recombinant H5 (rH5) in our Nanovax® (NE01) (rH5/NE01) adjuvant for intranasal vaccination in ferrets. We evaluated the regimen, one vs two immunization, and cross clade protection a ferr...
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Full title
A nanoemulsion-adjuvanted intranasal H5N1 influenza vaccine protects ferrets against homologous and heterologous H5N1 lethal challenge
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TN_cdi_proquest_miscellaneous_2287524830
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2287524830
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2019.08.071
