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Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory...

Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299135230

Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype

About this item

Full title

Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype

Publisher

US: Oxford University Press

Journal title

Inflammatory bowel diseases, 2020-02, Vol.26 (3), p.391-406

Language

English

Formats

Publication information

Publisher

US: Oxford University Press

More information

Scope and Contents

Contents

BackgroundThe inhibition of Janus kinases (JAKs) and subsequent signal transducers and activators of transcription (STATs) by tofacitinib represents a new therapeutic strategy in inflammatory bowel diseases (IBD) as clinical trials have led to approval of tofacitinib for ulcerative colitis (UC) and hint at a possible efficacy for Crohn`s disease (C...

Alternative Titles

Full title

Tofacitinib Reprograms Human Monocytes of IBD Patients and Healthy Controls Toward a More Regulatory Phenotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2299135230

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299135230

Other Identifiers

ISSN

1078-0998

E-ISSN

1536-4844

DOI

10.1093/ibd/izz213

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