A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation
A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation
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Zhao, Kang , Cheng, Sha , Miao, Na , Xu, Ping , Lu, Xiaohua , Zhang, Yuhan , Wang, Ming , Ouyang, Xuan , Yuan, Xun , Liu, Weiwei , Lu, Xin , Zhou, Peng , Gu, Jiaqi , Zhang, Yiqun , Qiu, Ding , Jin, Zhaohui , Su, Chen , Peng, Chao , Wang, Jian-Hua , Dong, Meng-Qiu , Wan, Youzhong , Ma, Jinbiao , Cheng, Hong , Huang, Ying and Yu, Yang
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In
Drosophila
, Panoramix enforces transcriptional silencing by binding to the target-engaged Piwi–piRNA complex, although the precise mechanisms by which this occurs remain elusive. Here, we show that Panoramix functions toget...
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A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation
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TN_cdi_proquest_miscellaneous_2299766548
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299766548
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-019-0396-0