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A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299766548

A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

About this item

Full title

A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2019-10, Vol.21 (10), p.1261-1272

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In
Drosophila
, Panoramix enforces transcriptional silencing by binding to the target-engaged Piwi–piRNA complex, although the precise mechanisms by which this occurs remain elusive. Here, we show that Panoramix functions toget...

Alternative Titles

Full title

A Pandas complex adapted for piRNA-guided transcriptional silencing and heterochromatin formation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2299766548

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2299766548

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-019-0396-0

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