Developing neoantigen-targeted T cell–based treatments for solid tumors
Developing neoantigen-targeted T cell–based treatments for solid tumors
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Stimulating an immune response against cancer through adoptive transfer of tumor-targeting lymphocytes has shown great promise in hematological malignancies, but clinical efficacy against many common solid epithelial cancers remains low. Targeting ‘neoantigens’—the somatic mutations expressed only by tumor cells—might enable tumor destruction witho...
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Full title
Developing neoantigen-targeted T cell–based treatments for solid tumors
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TN_cdi_proquest_miscellaneous_2302480275
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2302480275
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-019-0596-y
