The U1 spliceosomal RNA is recurrently mutated in multiple cancers
The U1 spliceosomal RNA is recurrently mutated in multiple cancers
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Cancers are caused by genomic alterations known as drivers. Hundreds of drivers in coding genes are known but, to date, only a handful of noncoding drivers have been discovered—despite intensive searching
1
,
2
. Attention has recently shifted to the role of altered RNA splicing in cancer; driver mutations that lead to transcriptome-wid...
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Full title
The U1 spliceosomal RNA is recurrently mutated in multiple cancers
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TN_cdi_proquest_miscellaneous_2303757268
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2303757268
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-019-1651-z