Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patie...
Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer
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Author / Creator
Liang, Chen , Shi, Si , Qin, Yi , Meng, Qingcai , Hua, Jie , Hu, Qiangshen , Ji, Shunrong , Zhang, Bo , Xu, Jin and Yu, Xian-Jun
Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Language
English
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Publisher
England: BMJ Publishing Group Ltd and British Society of Gastroenterology
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ObjectivePancreatic ductal adenocarcinoma (PDAC) is the most aggressive type of GI tumour, and it possesses deregulated cellular energetics. Although recent advances in PDAC biology have led to the discovery of recurrent genetic mutations in Kras, TP53 and SMAD4, which are related to this disease, clinical application of the molecular phenotype of...
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Full title
Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer
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TN_cdi_proquest_miscellaneous_2305803233
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2305803233
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ISSN
0017-5749,1468-3288
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2018-317163