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Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patie...

Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patie...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2305803233

Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer

About this item

Full title

Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer

Publisher

England: BMJ Publishing Group Ltd and British Society of Gastroenterology

Journal title

Gut, 2020-05, Vol.69 (5), p.888-900

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group Ltd and British Society of Gastroenterology

More information

Scope and Contents

Contents

ObjectivePancreatic ductal adenocarcinoma (PDAC) is the most aggressive type of GI tumour, and it possesses deregulated cellular energetics. Although recent advances in PDAC biology have led to the discovery of recurrent genetic mutations in Kras, TP53 and SMAD4, which are related to this disease, clinical application of the molecular phenotype of...

Alternative Titles

Full title

Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2305803233

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2305803233

Other Identifiers

ISSN

0017-5749,1468-3288

E-ISSN

1468-3288

DOI

10.1136/gutjnl-2018-317163

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