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The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic different...

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic different...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2308171157

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling

About this item

Full title

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2020-01, Vol.463 (1-2), p.203-210

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

As a m6A methylation modifier, METTL3 is functionally involved in various biological processes. Nevertheless, the role of METTL3 in osteogenesis is not determined up to date. In the current study, METTL3 is identified as a crucial regulator in the progression of osteogenic differentiation. Loss of METTL3 significantly augments calcium deposition an...

Alternative Titles

Full title

The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2308171157

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2308171157

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-019-03641-5

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