The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic different...
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling
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Author / Creator
Yu, Jinjin , Shen, Lujun , Liu, Yanli , Ming, Hong , Zhu, Xinxing , Chu, Maoping and Lin, Juntang
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
As a m6A methylation modifier, METTL3 is functionally involved in various biological processes. Nevertheless, the role of METTL3 in osteogenesis is not determined up to date. In the current study, METTL3 is identified as a crucial regulator in the progression of osteogenic differentiation. Loss of METTL3 significantly augments calcium deposition an...
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Full title
The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling
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Record Identifier
TN_cdi_proquest_miscellaneous_2308171157
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2308171157
Other Identifiers
ISSN
0300-8177
E-ISSN
1573-4919
DOI
10.1007/s11010-019-03641-5