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Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2314256305

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis

About this item

Full title

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis

Publisher

Cham: Springer Science and Business Media LLC

Journal title

Clinical Drug Investigation, 2020-02, Vol.40 (2), p.105-117

Language

English

Formats

Publication information

Publisher

Cham: Springer Science and Business Media LLC

More information

Scope and Contents

Contents

Background
Among the many consequences of loss of CFTR protein function, a significant reduction of the secretion of bicarbonate (HCO
3

) in cystic fibrosis (CF) is a major pathogenic feature. Loss of HCO
3

leads to abnormally low pH and impaired mucus clearance in airways and other exocrine organs, which suggests that NaHC...

Alternative Titles

Full title

Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2314256305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2314256305

Other Identifiers

ISSN

1173-2563,1179-1918

E-ISSN

1179-1918

DOI

10.1007/s40261-019-00861-x

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