Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms
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Author / Creator
Durham, Benjamin H. , Lopez Rodrigo, Estibaliz , Picarsic, Jennifer , Abramson, David , Rotemberg, Veronica , De Munck, Steven , Pannecoucke, Erwin , Lu, Sydney X. , Pastore, Alessandro , Yoshimi, Akihide , Mandelker, Diana , Ceyhan-Birsoy, Ozge , Ulaner, Gary A. , Walsh, Michael , Yabe, Mariko , Petrova-Drus, Kseniya , Arcila, Maria E. , Ladanyi, Marc , Solit, David B. , Berger, Michael F. , Hyman, David M. , Lacouture, Mario E. , Erickson, Caroline , Saganty, Ruth , Ki, Michelle , Dunkel, Ira J. , Santa-María López, Vicente , Mora, Jaume , Haroche, Julien , Emile, Jean-Francois , Decaux, Olivier , Geissmann, Frederic , Savvides, Savvas N. , Drilon, Alexander , Diamond, Eli L. and Abdel-Wahab, Omar
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Histiocytoses are clonal hematopoietic disorders frequently driven by mutations mapping to the BRAF and MEK1 and MEK2 kinases. Currently, however, the developmental origins of histiocytoses in patients are not well understood, and clinically meaningful therapeutic targets outside of BRAF and MEK are undefined. In this study, we uncovered activating...
Alternative Titles
Full title
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms
Authors, Artists and Contributors
Author / Creator
Lopez Rodrigo, Estibaliz
Picarsic, Jennifer
Abramson, David
Rotemberg, Veronica
De Munck, Steven
Pannecoucke, Erwin
Lu, Sydney X.
Pastore, Alessandro
Yoshimi, Akihide
Mandelker, Diana
Ceyhan-Birsoy, Ozge
Ulaner, Gary A.
Walsh, Michael
Yabe, Mariko
Petrova-Drus, Kseniya
Arcila, Maria E.
Ladanyi, Marc
Solit, David B.
Berger, Michael F.
Hyman, David M.
Lacouture, Mario E.
Erickson, Caroline
Saganty, Ruth
Ki, Michelle
Dunkel, Ira J.
Santa-María López, Vicente
Mora, Jaume
Haroche, Julien
Emile, Jean-Francois
Decaux, Olivier
Geissmann, Frederic
Savvides, Savvas N.
Drilon, Alexander
Diamond, Eli L.
Abdel-Wahab, Omar
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2318733263
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2318733263
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-019-0653-6