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Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2318733263

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Histiocytoses are clonal hematopoietic disorders frequently driven by mutations mapping to the BRAF and MEK1 and MEK2 kinases. Currently, however, the developmental origins of histiocytoses in patients are not well understood, and clinically meaningful therapeutic targets outside of BRAF and MEK are undefined. In this study, we uncovered activating...

Alternative Titles

Full title

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2318733263

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2318733263

Other Identifiers

ISSN

1078-8956,1546-170X

E-ISSN

1546-170X

DOI

10.1038/s41591-019-0653-6

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