Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, contr...
Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial
About this item
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Author / Creator
Coleman, Robert, Prof , Finkelstein, Dianne M, Prof , Barrios, Carlos, MD , Martin, Miguel, Prof , Iwata, Hiroji, MD , Hegg, Roberto, MD , Glaspy, John, Prof , Periañez, Alvaro Montaño, PhD , Tonkin, Katia, Prof , Deleu, Ines, MD , Sohn, Joohyuk, Prof , Crown, John, BCh , Delaloge, Suzette, MD , Dai, Tian, PhD , Zhou, Ying, PhD , Jandial, Danielle, MD and Chan, Arlene, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundDenosumab is a fully human monoclonal antibody that binds to, and inhibits, the receptor activator of RANKL (TNFSF11) and might affect breast cancer biology, as shown by preclinical evidence. We aimed to assess whether denosumab combined with standard-of-care adjuvant or neoadjuvant systemic therapy and locoregional treatments woul...
Alternative Titles
Full title
Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Finkelstein, Dianne M, Prof
Barrios, Carlos, MD
Martin, Miguel, Prof
Iwata, Hiroji, MD
Hegg, Roberto, MD
Glaspy, John, Prof
Periañez, Alvaro Montaño, PhD
Tonkin, Katia, Prof
Deleu, Ines, MD
Sohn, Joohyuk, Prof
Crown, John, BCh
Delaloge, Suzette, MD
Dai, Tian, PhD
Zhou, Ying, PhD
Jandial, Danielle, MD
Chan, Arlene, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2322740622
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2322740622
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(19)30687-4