In vitro apoptotic effect on human lymphatic filarial parasite by piperidine derivatives and thymidi...
In vitro apoptotic effect on human lymphatic filarial parasite by piperidine derivatives and thymidine reversal study
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Contents
A novel library of synthetic piperidine derivatives was used to screen against human lymphatic filarial parasite
Brugia malayi.
Piperidine has earlier been reported to have effect against parasites including rodent filarial nematodes. Compounds with hydroxyl substitutions (4Q and 4H) showed marked antifilarial effect. Molecular docking of 4H...
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Full title
In vitro apoptotic effect on human lymphatic filarial parasite by piperidine derivatives and thymidine reversal study
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Record Identifier
TN_cdi_proquest_miscellaneous_2322741666
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2322741666
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ISSN
0932-0113
E-ISSN
1432-1955
DOI
10.1007/s00436-019-06492-7