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Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against...

Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2327379315

Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against Staphylococcus aureus

About this item

Full title

Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against Staphylococcus aureus

Publisher

England

Journal title

Future medicinal chemistry, 2019-12, Vol.11 (24), p.3109-3124

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

To find alternative compounds against methicillin-resistant
(MRSA) and methicillin-susceptible
(MSSA), novel derivatives from dehydroabietic acid were synthesized.
Compound
was the most effective against 15 MRSA and 11 MSSA with minimum inhibitory concentration values ranging from 3.9 to 15.6 μg/ml. Although less active than
, compou...

Alternative Titles

Full title

Synthesis and structure-activity relationships of novel abietane diterpenoids with activity against Staphylococcus aureus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_2327379315

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2327379315

Other Identifiers

ISSN

1756-8919

E-ISSN

1756-8927

DOI

10.4155/fmc-2019-0192

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