Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer
Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer
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Full title
Author / Creator
PAOLA-1 Investigators , Ray-Coquard, Isabelle , Pautier, Patricia , Pignata, Sandro , Pérol, David , González-Martín, Antonio , Berger, Regina , Fujiwara, Keiichi , Vergote, Ignace , Colombo, Nicoletta , Mäenpää, Johanna , Selle, Frédéric , Sehouli, Jalid , Lorusso, Domenica , Guerra Alía, Eva M , Reinthaller, Alexander , Nagao, Shoji , Lefeuvre-Plesse, Claudia , Canzler, Ulrich , Scambia, Giovanni , Lortholary, Alain , Marmé, Frederik , Combe, Pierre , de Gregorio, Nikolaus , Rodrigues, Manuel , Buderath, Paul , Dubot, Coraline , Burges, Alexander , You, Benoît , Pujade-Lauraine, Eric and Harter, Philipp
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
When used as maintenance therapy, the PARP inhibitor olaparib provided a significant progression-free survival benefit in women with ovarian cancer who had a response to primary chemotherapy, particularly in those whose tumors were deficient in homologous recombination (e.g.,
BRCA
-mutated tumors). Hematologic toxic effects were observed.
Alternative Titles
Full title
Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer
Authors, Artists and Contributors
Author / Creator
Ray-Coquard, Isabelle
Pautier, Patricia
Pignata, Sandro
Pérol, David
González-Martín, Antonio
Berger, Regina
Fujiwara, Keiichi
Vergote, Ignace
Colombo, Nicoletta
Mäenpää, Johanna
Selle, Frédéric
Sehouli, Jalid
Lorusso, Domenica
Guerra Alía, Eva M
Reinthaller, Alexander
Nagao, Shoji
Lefeuvre-Plesse, Claudia
Canzler, Ulrich
Scambia, Giovanni
Lortholary, Alain
Marmé, Frederik
Combe, Pierre
de Gregorio, Nikolaus
Rodrigues, Manuel
Buderath, Paul
Dubot, Coraline
Burges, Alexander
You, Benoît
Pujade-Lauraine, Eric
Harter, Philipp
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2328773644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2328773644
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1911361
