Lipoprotein(a) Reduction in Persons with Cardiovascular Disease
Lipoprotein(a) Reduction in Persons with Cardiovascular Disease
About this item
Full title
Author / Creator
AKCEA-APO(a)-LRx Study Investigators , Tsimikas, Sotirios , Karwatowska-Prokopczuk, Ewa , Gouni-Berthold, Ioanna , Tardif, Jean-Claude , Baum, Seth J , Steinhagen-Thiessen, Elizabeth , Shapiro, Michael D , Stroes, Erik S , Moriarty, Patrick M , Nordestgaard, Børge G , Xia, Shuting , Guerriero, Jonathan , Viney, Nicholas J , O’Dea, Louis and Witztum, Joseph L
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Elevated levels of lipoprotein(a) in the plasma are a risk factor for cardiovascular disease, and lowering levels can be achieved with antisense oligonucleotide targeting
LPA
messenger RNA, which encodes lipoprotein(a). This trial tested whether the same effect can be achieved in persons with established cardiovascular disease.
Alternative Titles
Full title
Lipoprotein(a) Reduction in Persons with Cardiovascular Disease
Authors, Artists and Contributors
Author / Creator
Tsimikas, Sotirios
Karwatowska-Prokopczuk, Ewa
Gouni-Berthold, Ioanna
Tardif, Jean-Claude
Baum, Seth J
Steinhagen-Thiessen, Elizabeth
Shapiro, Michael D
Stroes, Erik S
Moriarty, Patrick M
Nordestgaard, Børge G
Xia, Shuting
Guerriero, Jonathan
Viney, Nicholas J
O’Dea, Louis
Witztum, Joseph L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_2332083989
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_2332083989
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1905239
